<OL TYPE="1"><LI>to make bitter<OL TYPE="a"><LI>to produce a bitter taste in the stomach</OL><LI>to embitter. exasperate<OL TYPE="a"><LI>render angry, indignant<LI>to be embittered, irritated<LI>to visit with bitterness, to grieve (deal bitterly with)</OL></OL>